Searchable abstracts of presentations at key conferences in endocrinology

ea0049gp3 | Adrenal 1 | ECE2017

Exosomal hsa-miR-483-5p and hsa-miR-101 are potential minimally invasive biomarkers of adrenocortical carcinoma

Perge Pal , Butz Henriett , Pezzani Raffaele , Bancos Irina , Nagy Zoltan , Decmann Abel , Luconi Michaela , Mannelli Massimo , Buzas Edit Iren , Toth Miklos , Boscaro Marco , Patocs Attila , Igaz Peter

Background: Extracellular vesicles (exosomes, microvesicles) shed from tumor cells containing microRNAs can be exploited as markers of malignancy. The preoperative diagnosis of adrenocortical malignancy is difficult and microRNAs have proved useful in the diagnosis of many tumors, including adrenocortical cancer (ACC), but there have no studies to date on extracellular vesicle associated microRNAs in ACC.Aim: To evaluate the diagnostic potential of extra...